Is it guaranteed that If I have an Express Entry Profile, I can come to Canada as PR ?

Having an Express Entry profile is no guarantee, that you will be invited. However having an Express Entry profile is a first step in the program to be invited.  Invitations are issued to various individuals from the pool. If you stay in the pool and your profile is active, you may be invited.  Only candidates having an active profile are invited to apply for PR under the Express Entry program.